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Salbutamol - Indications, Dosage, Side Effects And Precautions

Information about Salbutamol Generic Name : SalbutamolPronunciation : Sal-BYOU-tuh-mole Latest prescription information about Salbutamol. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list. ICD Code : Y55.6Therapeutic Classification : Anti- Asthmatics

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Trade Names/Brand Names of Salbutamol

India :  More... International :  Proventil, VoSpire ER, Ventolin

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Other Name(s) of Salbutamol

Albuterol

Why is Salbutamol Prescribed? (Indications)

This medication is a bronchodilator, prescribed for asthma and chronic obstructive pulmonary disease (COPD).  It works by relaxing and opening the air passages to the lungs to make breathing easier.

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When should Salbutamol not be taken? (Contraindications)

Contraindicated in patients with high blood pressure during pregnancy, uterine infection, miscarriage, heart disease, and hypersensitivity.

What is the dosage of Salbutamol?

PO- The recommended dose is 2 to 4 mg.IV/IM- 0.25 to 0.5mg.Inhaler- 100 to 200 mg by inhalation.

How should Salbutamol be taken?

It comes as a tablet to take by mouth, on an empty stomach.It also comes as a solution for injection to be administered by a healthcare provider into the vein or large muscle.It also comes as an inhaler to inhale by mouth.

What are the warnings and precautions for Salbutamol?

• Caution should be exercised in patients with history of heart problems, high blood pressure, diabetes, low levels of potassium in the blood, seizure, overactive thyroid, any allergy, who are taking other medication, during pregnancy and breastfeeding.

• Avoid alcohol consumption.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Salbutamol?

•   Central Nervous System : Nervousness, shakiness, dizziness, headache, over active and hoarseness.•   Musculoskeletal : Muscle cramps.•   Gastrointestinal : Nausea and increased or decreased appetite.•   Respiratory : Nosebleed and difficulty in breathing.•   Heart : Chest pain and irregular heart beat.•   Miscellaneous : Fever, pale skin, rash, hives and itching.

What are the other precautions for Salbutamol?

Avoid excess dosage.

What are the storage conditions for Salbutamol?

Store it at room temperature (30oC).

Schedule : HPrescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

Last Updated : Mar 2018


Side Effects Of Plaquenil: What You Need To Know

Plaquenil (hydroxychloroquine) is a prescription drug used for certain types of arthritis, lupus, and malaria. Plaquenil can cause side effects ranging from mild to serious. Examples include hair loss, rash, itching, and eye-related side effects.

Plaquenil is used in adults for:

Plaquenil is also used in certain children to treat and help prevent certain forms of malaria.

The active ingredient in Plaquenil is hydroxychloroquine. (An active ingredient is what makes a drug work.) The drug comes as a tablet that you swallow.

Keep reading to learn about the common, mild, and serious side effects (also called adverse effects) that Plaquenil can cause. For a general overview of the drug, including details about its uses, see this article.

NOT USED FOR COVID-19

Hydroxychloroquine, the active drug in Plaquenil, is not recommended for use in treating COVID-19 (the illness caused by the coronavirus SARS-CoV-2). Do not take any prescription drug, including Plaquenil, unless your doctor recommends that you do so.

For information about how to prepare, advice on prevention and treatment, and expert recommendations, visit our coronavirus hub.

Some people may experience mild or serious side effects during Plaquenil treatment. Examples of Plaquenil's most commonly reported side effects include:

Examples of mild side effects that have been reported with Plaquenil include:

* To learn more about this side effect, see the "Side effects explained" section below.

In most cases, these side effects should be temporary. And some may be easily managed, too. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. And don't stop taking Plaquenil unless your doctor recommends it.

Plaquenil may cause mild side effects other than the ones listed above. See the Plaquenil prescribing information for details.

Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. If you'd like to notify the FDA about a side effect you've had with Plaquenil, visit MedWatch.

Serious side effects that have been reported with Plaquenil include:

  • eye-related side effects*
  • severe skin-related side effects*
  • cardiac (heart-related) side effects*
  • ear-related side effects, such as tinnitus (ringing or buzzing in your ears), spinning sensations, or hearing loss
  • blood disorders, such as anemia (low red blood cell levels), neutropenia (low white blood cell levels), or thrombocytopenia (low platelet levels)
  • mental health problems, including mood changes, psychosis, and suicidal thoughts or behavior
  • liver problems, such as liver failure
  • low blood sugar level
  • muscle weakness or wasting
  • seizures
  • allergic reaction*†
  • * To learn more about this side effect, see the "Side effects explained" section below.† An allergic reaction is possible after taking Plaquenil. But it's not clear whether this side effect occurred in studies.

    If you develop serious side effects while taking Plaquenil, call your doctor right away. If the side effects seem life threatening or if you think you're having a medical emergency, immediately call 911 or your local emergency number.

    Get answers to some frequently asked questions about Plaquenil's side effects.

    Can Plaquenil cause weight gain?

    No, it's not likely. Weight gain isn't a known side effect of this drug. In fact, it may have the opposite effect. Loss of appetite and weight loss have been reported in some people taking Plaquenil. But it's not known how often these side effects occur.

    If you're concerned about Plaquenil and weight gain or weight loss, talk with your doctor. They can suggest ways to help you reach or maintain a body weight that's healthy for you.

    Will I have withdrawal symptoms if I stop taking Plaquenil?

    No, you shouldn't. Withdrawal symptoms are side effects that can happen when you stop taking a drug that your body is dependent on. (With dependence, your body needs the drug to feel like it usually does.) Your body doesn't become dependent on Plaquenil during treatment. So if you stop taking it, this won't cause withdrawal symptoms.

    If you take Plaquenil for lupus or rheumatoid arthritis, you may notice that stopping treatment makes your condition get worse. That's because Plaquenil doesn't cure these conditions, it only reduces their symptoms. So if you stop treatment, this can make your symptoms come back.

    But if you take Plaquenil to treat or help prevent malaria, you shouldn't notice any problems after stopping treatment.

    Does my risk of side effects depend on the dose of Plaquenil I take (200 mg, 400 mg, or 600 mg)?

    It might. As with many medications, taking high doses of Plaquenil may raise your risk of certain side effects. For example, taking higher doses of Plaquenil could raise your risk of certain eye-related and heart-related side effects. See "Side effects explained" below to read more about these.

    Ask your doctor what dosage of Plaquenil is recommended for your condition. They can tell you if this dosage has a higher risk of side effects than other dosages.

    Can Plaquenil cause long-term side effects? Will my risk of long-term side effects increase if I take the drug for a long time?

    Yes, Plaquenil can cause some long-term side effects. These are side effects that last for a long time or are permanent. Taking Plaquenil for long periods of time can raise your risk of developing certain long-term side effects.

    The main long-term side effects of Plaquenil are eye-related. Plaquenil can damage your retina, which may lead to permanent loss of vision. Retinal damage can sometimes continue to get worse even after you stop taking the medication. Taking Plaquenil long term raises your risk of developing retinal damage. To read more about this side effect, see "Side effects explained" below.

    Some other serious side effects of Plaquenil, such as certain heart problems, may also last a long time, even with treatment. Exactly how long side effects last will depend on how they respond to any treatments you may have for them. It's not known if taking Plaquenil long term raises your risk of other side effects.

    If you have questions about how long Plaquenil side effects may last, or your risk of long-term side effects, talk with your doctor.

    Are there any side effects specific to taking Plaquenil for lupus?

    No, there aren't any side effects that are specific to people taking Plaquenil for lupus. But if you have lupus, you'll likely need to take Plaquenil long term. And taking Plaquenil long term can raise your risk of certain side effects, such as retinal damage. See the question above to read more about this.

    Learn more about some of the side effects Plaquenil may cause.

    Eye-related side effects

    It's not known how often eye-related side effects happen with Plaquenil, but the drug can sometimes cause such side effects.

    These include damage to the retina, which is the light-sensitive tissue in the back of your eye. Damage to the retina can cause loss of vision that can be permanent.

    Symptoms of retinal damage may include:

  • decreased vision
  • trouble seeing in the dark
  • You may have a raised risk of retinal damage with Plaquenil if you:

  • take a high Plaquenil dosage
  • take the medication for longer than 5 years
  • have a disease affecting your macula (a small area in the center of your retina)
  • have kidney problems
  • take certain other medications
  • Other possible side effects of Plaquenil on eyes include macular degeneration and changes to the cornea, such as swelling or clouding. (The cornea is the front layer of your eye that lets in light.) These side effects can cause changes to your vision, such as blurry vision, double vision, halos around lights, and sensitivity to light. Plaquenil can also cause blind spots in your vision.

    What might help

    If you have any changes in your vision while taking Plaquenil or after stopping treatment, talk with your doctor right away. They may want you to have an eye exam.

    You should have an eye exam within 1 year of starting treatment with Plaquenil. During long-term treatment, you'll then have more eye exams to check if your vision has changed since starting Plaquenil.

    Eye exams are usually recommended every 5 years. But if you have a raised risk of retinal damage, these exams are recommended every year. Eye exams check for any damage to your retina and other problems with your vision.

    If you have certain eye side effects, in particular retinal damage, you'll need to stop taking Plaquenil. And your doctor may switch you to a different treatment for your condition.

    If you have retinal damage, your doctor will monitor you closely after you stop treatment. It's possible the damage may continue, and your vision might continue to get worse.

    If you're concerned about the risk of eye-related side effects with Plaquenil, talk with your doctor.

    Hair loss

    Some people may have hair loss while taking Plaquenil. But it's not known how often this side effect occurs.

    Hair loss can also be a symptom of lupus and rheumatoid arthritis (RA), which Plaquenil is prescribed to treat.

    Note that Plaquenil is occasionally prescribed to treat certain types of hair loss. But it's not known for sure if it's effective for this use.

    What might help

    If you have hair loss while taking Plaquenil, talk with your doctor. They can help work out the cause of your hair loss and suggest ways to help manage it.

    If you have hair loss that's caused by lupus or RA, you may find that Plaquenil lessens this side effect.

    If you have arthritis, you may wonder whether taking folic acid can help reduce hair loss with Plaquenil.

    Another drug commonly prescribed to treat RA, called methotrexate, often causes side effects such as hair loss. And doctors often prescribe folic acid with methotrexate to help reduce its side effects. Folic acid affects the way methotrexate works. However, taking folic acid with Plaquenil won't reduce hair loss associated with this medication.

    If you'd like to find out more about Plaquenil and hair loss, talk with your doctor.

    Dizziness

    You might have dizziness while taking Plaquenil. But it's not known how often this occurs.

    It's possible to have dizziness without any other symptoms. But dizziness can also be a symptom of other side effects of Plaquenil. These include ear-related side effects such as vertigo. With vertigo, you may also have nausea and a sensation of spinning.

    Dizziness can also be a symptom of some serious side effects of Plaquenil, such as low blood sugar and heart problems.

    What might help

    If you have dizzy spells while taking Plaquenil, lie down until the dizziness eases. And be sure to get up slowly.

    If you have dizziness that doesn't ease, or you often have dizzy spells, contact your doctor to get this checked. Your doctor can give further advice on what to do. They may also want to rule out more serious side effects.

    Rash, itching, and severe skin-related side effects

    It's not known how often skin-related side effects happen with Plaquenil, but they can occur.

    Plaquenil may cause a skin rash or itching. It may also make your skin more sensitive to sunlight or other UV light. This is called photosensitivity, and it can increase your risk of getting a sunburn.

    Plaquenil may also cause serious skin-related side effects. These include Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms (DRESS syndrome). These side effects can be life threatening.

    Symptoms of serious skin-related side effects include:

  • blisters in the mouth or on the skin, eyes, or lips
  • itching
  • burning sensation
  • peeling
  • widespread rash
  • fever
  • What might help

    While taking Plaquenil, it's important to protect your skin from UV light to avoid getting a sunburn. Don't use sunlamps and sunbeds, and protect your skin from sunlight with clothing. Use sunscreen on skin that's not covered.

    If you get a sunburn or rash, or experience itching while taking Plaquenil, talk with your doctor. They can recommend ways to manage these side effects. For example, they may suggest using a moisturizer or mild steroid cream, or taking an antihistamine.

    However, if you have symptoms of a serious skin-related side effect, contact your doctor right away. If your doctor diagnoses a serious skin reaction from Plaquenil, you'll need to stop taking the medication.

    Cardiac (heart-related) side effects

    Plaquenil can sometimes cause heart-related side effects. These include cardiomyopathy (weakening of your heart muscle), heart failure, and irregular heart rhythm. These side effects can be life threatening. It's not known how often they occur.

    You may have a raised risk of heart-related side effects with Plaquenil if you have:

    Taking certain other medications may also increase your risk of these side effects.

    Symptoms of heart-related side effects may include:

  • feeling that your heart is racing, pounding, or skipping beats
  • fast or irregular heartbeat
  • feeling dizzy or lightheaded
  • fainting
  • fatigue (low energy)
  • shortness of breath
  • swollen ankles or feet
  • What might help

    Before prescribing Plaquenil, your doctor will assess if it's safe for you to take. Talk with your doctor about any heart problems you may have. Also talk with them about any medications you take.

    While taking Plaquenil, contact your doctor right away if you have any symptoms of heart-related side effects. But if your symptoms feel life threatening, call 911 or your local emergency number.

    If your doctor confirms that you do have heart-related side effects from Plaquenil, you'll need to stop taking the medication.

    Allergic reaction

    Like most drugs, Plaquenil can cause an allergic reaction in some people. But it's not clear whether this side effect occurred in studies.

    Symptoms may be mild or serious and can include:

  • skin rash
  • itchiness
  • flushing (temporary warmth, redness, or deepening of skin color)
  • swelling under your skin, typically in your eyelids, lips, hands, or feet
  • swelling of your mouth, tongue, or throat, which can make it hard to breathe
  • What might help

    If you have mild symptoms of an allergic reaction, such as a mild rash, contact your doctor right away. To manage your symptoms, they may suggest an over-the-counter antihistamine you take by mouth, such as Benadryl (diphenhydramine). Or they may recommend a product you apply to your skin, such as hydrocortisone cream.

    If your doctor confirms you had a mild allergic reaction to Plaquenil, they'll decide if you should continue taking it.

    If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms could be life threatening and require immediate medical care.

    If your doctor confirms you had a serious allergic reaction to Plaquenil, they may have you switch to a different treatment.

    Keeping track of side effects

    During Plaquenil treatment, consider keeping notes on any side effects you're having. Then, you can share this information with your doctor. This is especially helpful to do when you first start taking new drugs or using a combination of treatments.

    Your side effect notes can include things such as:

  • what dose of the drug you were taking when you had the side effect
  • how soon after starting that dose you had the side effect
  • what your symptoms were from the side effect
  • how it affected your daily activities
  • what other medications you were also taking
  • any other information you feel is important
  • Keeping notes and sharing them with your doctor will help your doctor learn more about how Plaquenil affects you. And your doctor can use this information to adjust your treatment plan if needed.

    Plaquenil may not be right for you if you have certain medical conditions or other factors that affect your health. Talk with your doctor about your health history before you take Plaquenil. The list below includes factors to consider.

    Allergic reaction. If you've had an allergic reaction to Plaquenil or any of its ingredients, you shouldn't take Plaquenil. In addition, you shouldn't take Plaquenil if you've ever had an allergic reaction to similar drugs, called 4-aminoquinolines. An example is chloroquine. Ask your doctor what other medications are better options for you.

    Heart problems. Plaquenil can cause heart-related side effects. If you have a heart problem, ask your doctor if Plaquenil is safe for you. Examples of heart problems include heart disease, such as heart failure, or a past heart attack. They also include heart rate or rhythm problems, such as a slow or irregular heartbeat.

    Electrolyte levels. If you have low levels of potassium or magnesium in your blood, you could have a raised risk of certain heart-related side effects with Plaquenil. Your doctor will prescribe medication to increase your potassium or magnesium levels before you start Plaquenil.

    Kidney or liver problems. Kidney or liver problems can raise your risk of side effects with Plaquenil. In addition, Plaquenil can also make liver problems worse. If you have kidney or liver problems, your doctor may prescribe a dosage of Plaquenil that's lower than usual.

    Psoriasis or porphyria. Taking Plaquenil could worsen psoriasis or porphyria in some people. If you have either of these conditions, talk with your doctor about whether this medication is right for you.

    Blood disorders. Taking Plaquenil could worsen blood disorders, such as anemia (low red blood cell levels), neutropenia (low white blood cell levels), or thrombocytopenia (low platelet levels). If you have a blood disorder, you'll need frequent blood tests to check your blood cell levels while taking Plaquenil. If Plaquenil makes your condition worse, you'll need to stop taking it.

    Glucose-6-phosphate dehydrogenase (G6PD) deficiency. G6PD is a protein that helps red blood cells work correctly. In a person who has a deficiency of G6PD, taking Plaquenil could make red blood cells break down. This could lead to low levels of red blood cells. If you have G6PD deficiency, talk with your doctor about whether Plaquenil is safe for you. You may need frequent blood tests while taking this medication.

    History of mental health problems. Plaquenil can sometimes cause psychiatric side effects such as psychosis, worsening depression, and suicidal thoughts and actions. If you have a history of depression or other mental health problems, talk with your doctor about whether Plaquenil is right for you.

    Diabetes. Plaquenil can sometimes cause low blood sugar. If you're taking diabetes medication, you may have a raised risk of this side effect. Talk with your doctor about whether you should monitor your blood sugar while taking Plaquenil.

    Neurological disorders. Plaquenil can sometimes cause seizures or problems with movement, such as tremors or twitching.If you have a neurological disorder (a condition affecting your brain and nerves), taking Plaquenil could worsen the symptoms of your condition. Talk with your doctor about whether Plaquenil is right for you.

    Alcohol and Plaquenil

    Drinking alcohol with Plaquenil could raise your risk of certain side effects. These include nausea, diarrhea, dizziness, and liver problems.

    If you drink alcohol, talk with your doctor about how much is safe for you to consume while you're taking Plaquenil.

    Pregnancy and breastfeeding while taking Plaquenil

    It's not known for sure if Plaquenil is safe to take during pregnancy. If you're pregnant or plan to become pregnant, talk with your doctor about the possible risks and benefits of taking Plaquenil.

    Small amounts of Plaquenil can pass into breast milk. Side effects haven't been reported in children who are breastfed by people taking the drug. However, if you're breastfeeding or plan to breastfeed, talk with your doctor about the best way to feed your child while taking Plaquenil.

    Most side effects of Plaquenil are mild and easily managed. However, this medication does have a risk of some serious side effects, so it's not suitable for everyone.

    If you'd like to know more about Plaquenil's possible side effects and your risk of having problems with this medication, talk with your doctor. They can help you decide if Plaquenil is a good treatment option for you.

    Examples of some questions you might want to ask your doctor include:

  • Am I at a higher risk of side effects with Plaquenil than other people?
  • Is there anything I can do to reduce my risk of side effects?
  • Are side effects less common when Plaquenil is taken to help prevent malaria?
  • Do my other medications raise my risk of side effects with Plaquenil?
  • Will Plaquenil affect my ability to drive?
  • To learn more about Plaquenil, see these articles:

    To get information on different conditions and tips for improving your health, subscribe to any of Healthline's newsletters. You may also want to check out the online communities at Bezzy. It's a place where people with certain conditions can find support and connect with others.

    Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.


    Side Effects Of Vraylar

    Vraylar (cariprazine) is a brand-name oral capsule that's prescribed for certain mental health conditions, such as major depressive disorder (often referred to as depression). As with other drugs, Vraylar can cause side effects, such as nausea, insomnia, and uncontrolled body movements.

    Vraylar belongs to a drug class called atypical antipsychotics. The drug is not available in a generic version.

    Read on to learn about potential common, mild, and serious side effects of Vraylar. For a general overview of the drug, including details about its uses, see this article.

    Certain side effects have been reported when taking Vraylar, some of which were more common than others. These side effects may be temporary, lasting a few days or weeks. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.

    These are a few of the more common side effects reported by people who took Vraylar in clinical trials:

  • difficulty moving or slowed movements
  • uncontrolled body movements*
  • tremors
  • restlessness
  • sleepiness
  • * For more about this side effect, refer to the "Side effect specifics" section below.

    Mild side effects can occur with Vraylar use. This list doesn't include all possible mild side effects of the drug. For more information, you can refer to Vraylar's prescribing information.

    Mild side effects that have been reported with Vraylar use include:

    These side effects may be temporary, lasting a few days or weeks. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.

    Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. If you develop a side effect while taking Vraylar and want to tell the FDA about it, visit MedWatch.

    * To learn more about this side effect, see the "Vraylar and weight gain" section below.† For more about this side effect, refer to the "Side effect specifics" section below.

    Vraylar may cause serious side effects. The list below may not include all possible serious side effects of the drug. For more information, you can refer to Vraylar's prescribing information.

    If you develop serious side effects while taking Vraylar, call your doctor right away. If the side effects seem life threatening or you think you're having a medical emergency, immediately call 911 or your local emergency number.

    Serious side effects that have been reported and their symptoms can include:

  • Neuroleptic malignant syndrome (a serious reaction to certain drugs that requires immediate medical attention). Symptoms can include:
  • Type 2 diabetes and high blood sugar. Symptoms can include:
  • feeling very thirsty or very hungry
  • feeling weak, confused, or tired
  • needing to urinate more often than usual
  • Orthostatic hypotension (drop in blood pressure when you rise from sitting or lying down). Symptoms can include:
  • falling
  • feeling lightheaded
  • blurry vision
  • Falls due to other side effects, such as dizziness or orthostatic hypotension.
  • Seizures. Symptoms can include:
  • uncontrollable muscle spasms
  • falling
  • loss of consciousness followed by confusion
  • Leukopenia (low levels of white blood cells). Symptoms can include:
  • Difficulty swallowing, which could cause aspiration (food or liquid entering your airway).
  • Problems managing your body temperature, particularly when exercising or in hot weather. Symptoms can include:
  • Increased levels of triglycerides and cholesterol in your blood, which typically don't cause symptoms other than abnormal lab test results.
  • Uncontrolled body movements.*
  • Increased risk of death when used to treat psychosis related to dementia in older adults.†
  • Risk of suicidal thoughts and behaviors.†
  • Allergic reaction.*‡
  • * For more about this side effect, refer to the "Side effect specifics" section below.† Vraylar has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA). For more about this side effect, refer to the "Side effect specifics" section below.‡ An allergic reaction is possible after using Vraylar. But it's not clear whether this side effect occurred in clinical trials.

    Weight gain is a possible side effect from treatment with drugs classified as atypical antipsychotics, including Vraylar.

    However, weight gain wasn't common in clinical trials of Vraylar. And it was usually mild when it did occur.

    Your doctor will typically measure your body weight before you start taking Vraylar. They'll also monitor your weight during treatment. If your doctor determines that Vraylar could be causing weight gain, they may have you switch to a different medication.

    If you have concerns about your weight while taking Vraylar, talk with your doctor. They can recommend ways to help maintain a weight that's healthy for you.

    Vraylar may cause several side effects. Here are some frequently asked questions about the drug's side effects and their answers.

    Do Vraylar side effects go away? Are there any long-term side effects?

    Most side effects from Vraylar go away, either after a few days or once you stop taking the drug.

    However, some side effects can be long term. Uncontrolled body movements caused by Vraylar may not disappear, even if you stop taking the medication. (Uncontrolled body movements may also be known as tardive dyskinesia.)

    Vraylar may also cause type 2 diabetes, which may not go away, even if you stop using the drug.

    If you're experiencing side effects from Vraylar, especially ones that don't disappear after a few days, talk with your doctor. They may suggest switching to a different medication.

    Are sexual side effects possible with Vraylar use?

    Sexual side effects weren't reported by people using Vraylar in clinical trials. Sexual problems, such as changes in sex drive, are known side effects of some other antipsychotic drugs. But Vraylar isn't known to cause them. (Vraylar is a type of antipsychotic drug.)

    If you have sexual problems that concern you, talk with your doctor. They can help advise you on the proper treatment.

    Is weight loss a side effect of Vraylar?

    No, weight loss isn't a side effect of Vraylar. People taking Vraylar have sometimes reported weight gain* as a side effect, but not weight loss.

    If you're concerned about your weight, talk with your doctor. They can recommend ways to help maintain weight that's healthy for you.

    * For information on weight gain, see the "Vraylar and weight gain" section above.

    Can Vraylar cause brain fog?

    Vraylar wasn't reported to specifically cause brain fog. But it's possible that the drug could cause side effects that would be considered to be brain fog. Another name for brain fog is mental fatigue.

    Brain fog isn't a medical condition. But it can be a symptom of other conditions or a side effect of certain medications.

    In clinical trials, Vraylar caused some side effects that are similar to symptoms of brain fog. These side effects included sleepiness and fatigue.

    Keep in mind that brain fog can be a symptom of the conditions Vraylar is used to treat. For example, people with bipolar I disorder may have trouble concentrating during a depressive episode.

    If you experience brain fog while taking Vraylar, talk with your doctor. They may recommend ways to help ease it. They may also recommend a different medication for your condition.

    Are any side effects specific to Vraylar strengths?

    The different strengths of Vraylar aren't known to cause different side effects. The drug is available in four strengths: 1.5 milligrams (mg), 3 mg, 4.5 mg, and 6 mg.

    Some side effects were more or less common in people taking certain doses of Vraylar in clinical trials. However, the rates of side effects may be slightly different, depending on your Vraylar dose.

    If you have questions about the various strengths of Vraylar and possible side effects, talk with your doctor or pharmacist.

    Learn more about some of the side effects that Vraylar may cause.

    Nausea

    Nausea is a potential mild side effect from taking Vraylar. Nausea was among the more common side effects reported by people using the drug in clinical trials. But most people taking Vraylar didn't experience it.

    For most people who experience nausea from Vraylar, this side effect goes away on its own after a few days.

    What you can do

    If you experience nausea that doesn't go away after a few days while taking Vraylar, talk with your doctor. They'll typically want to see you for an appointment so they can find out whether anything else could be causing the nausea. If your doctor determines that the nausea is a side effect of Vraylar, they may suggest ways to ease it. But if the nausea is affecting your daily life, your doctor will typically recommend a different medication for your condition.

    Insomnia

    Insomnia is a possible side effect of taking Vraylar. Insomnia is a condition in which you have difficulty sleeping. People who took Vraylar reported symptoms such as:

  • difficulty falling asleep or staying asleep
  • trouble falling asleep after waking in the middle of the night or very early in the morning
  • What you can do

    If you experience insomnia while taking Vraylar, talk with your doctor. They may recommend different options. One is treatment for this side effect, such as a medication to help you sleep. Your doctor may recommend changes to your sleep hygiene, such as avoiding TV and phones before bed. Another option they may also suggest is switching to a different drug for your condition.

    Uncontrolled body movements

    Although rare, taking Vraylar can cause a serious side effect called tardive dyskinesia. It refers to uncontrolled body movements that are repetitive.

    Symptoms of tardive dyskinesia can include:

  • chewing motions
  • jerky movements of your arms, legs, or torso
  • lip smacking
  • puffing air into your cheeks
  • tongue twisting
  • Tardive dyskinesia symptoms may go away after you stop taking Vraylar. But this side effect can sometimes be permanent.

    It isn't possible to predict who develops tardive dyskinesia with Vraylar. But it's believed that older adults, particularly older females,* are at a higher risk. Both your risk for developing tardive dyskinesia and having it be permanent rise the longer you use Vraylar.

    Taking a higher dose can also increase your risk, but in rare cases, tardive dyskinesia has occurred in people taking low doses. In addition, it's possible to develop tardive dyskinesia after stopping Vraylar treatment because the drug stays in your body for a long time.

    * Sex and gender exist on spectrums. Use of the term "female" in this article refers to sex assigned at birth.

    What you can do

    Your doctor will monitor you while you're taking Vraylar to see whether the drug is effective and whether you have any side effects. They'll try to prescribe the lowest dose that works for you.

    While taking Vraylar, watch for symptoms of tardive dyskinesia and talk with your doctor if you develop any of them. They'll likely want to discuss with you the pros and cons of continuing to take the drug. For some people, Vraylar is the best long-term treatment for their condition, even when tardive dyskinesia occurs. For other people, tardive dyskinesia may be a reason to stop taking Vraylar and switch to a different medication.

    Increased risk of death in older adults who have psychosis due to dementia

    Vraylar has a boxed warning for an increased risk of death when taken by older adults ages 65 and over who have psychosis due to dementia. A boxed warning is the strongest warning that the Food and Drug Administration (FDA) requires. Boxed warnings alert patients and doctors about potentially dangerous drug effects.

    Psychosis refers to a changed sense of reality. And with dementia, people have problems with memory, thinking, and communication.

    Older adults with psychosis related to dementia have a higher risk for death when treated with antipsychotic medications, including Vraylar.

    What you can do

    Vraylar is not FDA-approved for treating psychosis caused by dementia in older adults. If an older adult has psychosis due to dementia and you're interested in treatments for them, talk with their doctor.

    Suicidal thoughts and behaviors

    Vraylar has a boxed warning for the risk of suicidal thoughts and behaviors in children and young adults under age 25. A boxed warning is the strongest warning that the FDA requires. Boxed warnings alert patients and doctors about potentially dangerous drug effects.

    Antidepressants may increase the risk of suicidal thoughts and behaviors in children and young adults. Vraylar is a type of antipsychotic drug. But when Vraylar is used to treat depressive episodes in bipolar I disorder or major depressive disorder (MDD), it may act similarly to antidepressants. (Note that Vraylar is taken together with an antidepressant for treating MDD.)

    Vraylar is not approved for use in people younger than age 18 years. However, whatever your age, your doctor will typically monitor you while you take drugs such as Vraylar. They'll watch for changes in thinking, including suicidal thoughts or behaviors.

    What you can do

    During your Vraylar treatment, watch for changes in your thoughts and behaviors. You can also ask friends and loved ones to monitor you. This is especially important when you first start taking the medication and whenever your dose is adjusted. If you or someone else notices any changes, talk with your doctor immediately or get emergency medical attention right away.

    Allergic reaction

    As with most drugs, Vraylar can cause an allergic reaction in some people. But it's not clear whether this side effect occurred in clinical trials.

    Symptoms can be mild or serious and can include:

  • rash
  • itching
  • flushing
  • swelling under your skin, typically in your lips, eyelids, feet, or hands
  • swelling of your mouth, tongue, or throat, which can make it hard to breathe
  • What you can do

    For mild symptoms of an allergic reaction, call your doctor right away. They may recommend ways to ease your symptoms and determine whether you should keep taking Vraylar. But if your symptoms are serious and you think you're having a medical emergency, immediately call 911 or your local emergency number.

    Below are precautions to consider before you take Vraylar.

    Boxed warnings

    This drug has boxed warnings. One is about the increased risk of death in older adults who have psychosis due to dementia. The other boxed warning is about suicidal thoughts and behaviors. These are serious warnings from the Food and Drug Administration (FDA). For details, see the "Side effect specifics" section above.

    Other precautions

    Be sure to talk with your doctor about your health history before you take Vraylar. This drug may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. The conditions and factors to consider include the following:

    Diabetes. Vraylar may cause type 2 diabetes and high blood sugar as a side effect. If you already have type 2 diabetes, you may find it harder to manage your blood sugar while taking Vraylar. Before you take Vraylar, be sure to talk with your doctor about the best way to treat your type 2 diabetes.

    High or low blood pressure. Vraylar may cause changes in blood pressure. As a result, it may worsen blood pressure problems. If you have problems with blood pressure, tell your doctor. This will help them determine whether Vraylar is right for you.

    High levels of triglycerides or cholesterol. Vraylar may cause high levels of triglycerides or cholesterol as a side effect. If you already have elevated levels of these fats, you may find it harder to manage your condition while using Vraylar. Your doctor will regularly check these levels while you're taking the drug. They may recommend treatment if your levels become too high.

    Kidney or liver problems. Vraylar hasn't been studied in people with severe kidney or severe liver problems, such as chronic kidney disease or hepatitis. Talk with your doctor about whether Vraylar is right for you if you have kidney or liver problems.

    Low levels of white blood cells. Taking Vraylar may cause leukopenia. If you already have low levels of white blood cells, you may be at a higher risk. Your doctor will monitor your levels of white blood cells while you're using Vraylar. They may have you stop taking the medication if the levels become too low.

    Seizures. Although rare, Vraylar can cause seizures as a side effect. You're more at risk for this side effect if you have epilepsy or had seizures in the past. Talk with your doctor about whether Vraylar is the right treatment for you.

    Allergic reaction. You should not take Vraylar if you've ever had an allergic reaction to Vraylar or any of its ingredients. Talk with your doctor about which other treatments are better choices for you.

    Alcohol with Vraylar

    There are no known interactions between Vraylar and alcohol.

    However, drinking alcohol may increase your risk for certain side effects of Vraylar, such as sleepiness and fatigue. If you drink alcohol, talk with your doctor about how much alcohol is safe for you to consume while you're taking Vraylar.

    Pregnancy and breastfeeding while taking Vraylar

    Here's some information about taking Vraylar while pregnant or breastfeeding.

    Pregnancy. It's not known whether it's safe to take Vraylar while pregnant. Talk with your doctor about treatment options for your condition if you're pregnant or planning to become pregnant.

    If you do choose to use Vraylar while pregnant, keep in mind that there's a pregnancy registry available. The registry gathers health information about how drugs such as Vraylar can affect pregnancy. This information may help others decide if Vraylar treatment is right for them. If you're interested in joining the pregnancy registry, talk with your doctor or visit the pregnancy registry site.

    Breastfeeding. It's not known whether Vraylar passes into breast milk. Talk with your doctor about the feeding options available for you and your child while taking Vraylar. Your doctor may also suggest trying a different medication.

    Side effects from Vraylar aren't common. And, when they do occur, they're usually mild. Most mild side effects of the drug go away with time and don't require medical attention.

    But you should talk with your doctor if you experience symptoms of serious side effects. They could require medical attention. These serious side effects include:

    It's important to note that antipsychotic medications such as Vraylar can increase the risk of death when used to treat psychosis related to dementia in older adults.* Vraylar should not be used to treat this condition.

    You should also talk with your doctor if you become pregnant while taking Vraylar.

    * Vraylar has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA). For details, see the "Side effect specifics" section above.

    To learn more

    If you'd like to learn more about Vraylar, talk with your doctor or pharmacist. They can help answer any questions you have about side effects from taking the drug.

    Besides talking with your doctor, you can do some research on your own. These articles might help:

    Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.






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