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Side Effect(s) Of Valacyclovir

Review the side-effects of Valacyclovir as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental. If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist. Most Common- Headache, abdominal pain, pain in the lower back region, weakness, swelling in the face, lip, tongue and throat region.

Respiratory - Difficulty in breathing.

Skin - Hives and red spots in the skin.

Gastrointestinal - Bloody diarrhea, vomiting and nausea.

Central Nervous System- Fainting, drowsiness, mood changes, convulsions, confusion, aggression and hallucinations.

Eye - Vision problems.

Miscellaneous- Photosensitivity, liver function abnormalities, depression, joint pain, stuffy nose and sore throat.

Other Precautions : * Avoid sexual contact with your life partner, if you have symptoms of genital herpes.* Do not stop the medication without consulting with your doctor.

Side Effects Of Eliquis: What You Need To Know

Eliquis (apixaban) is a prescription drug that treats or helps prevent blood clots in certain situations. Eliquis can cause side effects that range from mild to serious. Examples include nausea and bleeding.

Eliquis is used in adults to treat or prevent certain blood clots. Examples of the blood clots the drug treats include:

It's also used to prevent blood clots and stroke in people with a certain kind of atrial fibrillation.

The active ingredient in Eliquis is apixaban. (An active ingredient is what makes a drug work.) The drug comes as a tablet that you swallow. Your doctor may refer to Eliquis as a blood thinner.

Keep reading to learn about the common, mild, and serious side effects (also called adverse effects) that Eliquis can cause. For a general overview of the drug, including details about its uses, see this article.

Some people may experience mild to serious side effects during their Eliquis treatment. Examples of commonly reported side effects of Eliquis include:

* To learn more about this side effect, see the "Side effects explained" section below.

Examples of mild side effects that have been reported with Eliquis include:

* To learn more about this side effect, see the "Side effects explained" section below.

In most cases, these side effects should be temporary. And some may be easily managed. But if you have any symptoms that are ongoing or bother you, talk with your doctor or pharmacist. And do not stop taking Eliquis unless your doctor recommends it.

Eliquis may cause mild side effects other than the ones listed above. See the drug's prescribing information for details.

Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. If you'd like to notify the FDA about a side effect you've had with Eliquis, visit MedWatch.

Mild side effects are common in people taking Eliquis. But it's also possible to develop serious side effects from this medication. Serious side effects that have been reported with Eliquis include:

* Eliquis has a boxed warning for this side effect. This is the most serious warning from the Food and Drug Administration (FDA). To learn more, see the "Side effects explained" section below.† To learn more about this side effect, see the "Side effects explained" section below.

If you develop serious side effects while taking Eliquis, call your doctor right away. If the side effects seem life threatening or you think you're having a medical emergency, immediately call 911 or your local emergency number.

Get answers to some frequently asked questions about the side effects of Eliquis.

Do older people have a higher risk of side effects from Eliquis?

No, older people do not seem to have a higher risk of side effects from Eliquis than younger people.

In studies, the majority of people taking Eliquis were ages 65 years and older. The studies did not find an increased risk of Eliquis side effects in older people when compared with younger people.

But older people are more likely to have medical conditions than younger people. Having certain medical conditions may increase the risk of side effects from taking Eliquis. For more information, see the "Warnings for Eliquis" section below.

If you have questions about your risk of side effects from Eliquis, ask your doctor.

Am I at higher risk of side effects if I take the 5-mg strength of Eliquis?

Yes, you may be at a higher risk of side effects if you take a higher strength of Eliquis.

The drug is available in strengths of 2.5 milligrams (mg) and 5 mg. You'll take Eliquis twice per day. But depending on the dosage your doctor prescribes for your condition, you may take as much as 20 mg per day.

If you're concerned about side effects that you may have while taking a higher dosage of Eliquis, talk with your doctor or pharmacist. They can discuss your risk of side effects with you.

Can stopping Eliquis treatment suddenly cause side effects, such as withdrawal symptoms?

No, you shouldn't experience withdrawal symptoms if you stop taking Eliquis suddenly. (Withdrawal symptoms are side effects that can occur when you stop taking a drug that your body has become dependent on.) But stopping Eliquis treatment suddenly can increase your risk of blood clots.

In fact, Eliquis has a boxed warning for the risk of blood clots if you stop Eliquis too early. Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA). They alert doctors and patients about drug effects that may be dangerous. For more information on this boxed warning, see the "Side effects explained" section below.

You shouldn't stop taking Eliquis suddenly without talking with your doctor. They'll be able to recommend when to stop taking the drug. If you do need to suddenly stop taking Eliquis, your doctor may suggest a different medication for your condition.

Does Eliquis cause kidney-related side effects?

It's possible for Eliquis to cause kidney-related side effects. But kidney-related side effects were not commonly reported in studies of the drug.

In rare cases, Eliquis may cause serious bleeding. This includes bleeding in your organs, such as your kidneys.

Another rare side effect of Eliquis is blood in the urine, which could be due to a kidney-related problem.

If you're concerned about kidney-related side effects occurring during Eliquis treatment, talk with your doctor or pharmacist.

Learn more about some of the side effects Eliquis may cause.

Risk of blood clots if stopping Eliquis treatment early

Eliquis has a boxed warning for the risk of blood clots if stopping Eliquis treatment early. Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA). They alert doctors and patients about drug effects that may be dangerous.

Eliquis works to prevent blood clots from occurring or to treat a blood clot that you already have. But if you stop taking Eliquis before it's recommended, you may have an increased risk of blood clots.

What might help

Do not stop taking Eliquis without first talking with your doctor. If you do need to stop treatment with Eliquis, your doctor may recommend that you take a different blood thinner. This can help to prevent blood clots.

For more information about this side effect, talk with your doctor or pharmacist.

Risk of spinal blood clots from certain spinal procedures

Eliquis has a boxed warning for the risk of spinal blood clots from certain spinal procedures. Boxed warnings are the most serious warnings from the FDA. They alert doctors and patients about drug effects that may be dangerous.

Having certain spinal procedures during Eliquis treatment may increase the risk of blood clots in your spine. Symptoms of blood clots in your spine include:

What might help

Before having any spinal procedures done, tell your doctor that you're taking Eliquis. They may recommend scheduling your procedure when you'll have the least amount of Eliquis in your body. This can help decrease your risk of spinal blood clots.

Your doctor will also monitor you for symptoms of blood clots after you have a spinal procedure. If you have any of the symptoms listed above, contact your doctor or go to a hospital right away.

If you have concerns about risk of spinal blood clots during Eliquis treatment, talk with your doctor or pharmacist.

Nosebleeds

You may have nosebleeds during your treatment with Eliquis. But in studies, nosebleeds were not a commonly reported side effect in people taking Eliquis.

What might help

If you have nosebleeds during your treatment with Eliquis, talk with your doctor. They may be able to recommend ways to treat this side effect. For example, they may recommend using saline nasal spray to help moisten your nose, which may prevent nosebleeds.

Bruising

When you take Eliquis, you may notice that you bruise easier or more often than usual. Bruising was a common side effect reported by people in studies of Eliquis.

What might help

If you notice bruising during your treatment with Eliquis, talk with your doctor. If this side effect is severe or bothersome to you, your doctor may be able to recommend ways to help prevent it.

Allergic reaction

Like most drugs, Eliquis can cause an allergic reaction in some people.

Symptoms can be mild to serious and can include:

  • skin rash
  • itchiness
  • flushing (temporary warmth, redness, or deepening of skin color)
  • swelling under your skin, usually in your eyelids, lips, hands, or feet
  • swelling of your mouth, tongue, or throat, which can make it hard to breathe
  • What might help

    If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. They may suggest a treatment to manage your symptoms. Examples include:

  • an antihistamine you take by mouth, such as Benadryl (diphenhydramine)
  • a product you apply to your skin, such as hydrocortisone cream
  • If your doctor confirms you've had a mild allergic reaction to Eliquis, they'll decide if you should continue using it.

    If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms could be life threatening and require immediate medical care.

    If your doctor confirms you've had a serious allergic reaction to Eliquis, they may have you switch to a different treatment.

    Keeping track of side effects

    During your Eliquis treatment, consider taking notes on any side effects you're having. You can then share this information with your doctor. This is especially helpful when you first start taking new drugs or using a combination of treatments.

    Your side effect notes can include things such as:

  • what dose of the drug you were taking when you had the side effect
  • how soon you had the side effect after starting that dose
  • what your symptoms were
  • how it affected your daily activities
  • what other medications you were taking
  • any other information you feel is important
  • Keeping notes and sharing them with your doctor will help them learn more about how Eliquis affects you. They can then use this information to adjust your treatment plan if needed.

    Eliquis comes with several warnings, which may affect whether the drug is a good treatment for your condition.

    Before you start treatment with Eliquis, tell your doctor about any medical conditions that you have. This can help them determine if the drug is a safe treatment option for you.

    Boxed warnings

    Eliquis has boxed warnings for the risk of blood clots if stopping Eliquis treatment early and risk of spinal blood clots from certain spinal procedures. Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA). They alert doctors and patients about drug effects that may be dangerous.

  • Risk of blood clots if stopping Eliquis treatment early. You may have an increased risk of blood clots if you stop taking Eliquis early. It is not recommended that you stop taking this medication without first talking with your doctor.
  • Risk of spinal blood clots from certain spinal procedures. If you're taking Eliquis, you may have an increased risk of spinal blood clots after certain spinal procedures. Before you have any spinal procedures, tell your doctor that you're taking Eliquis.
  • To learn more, see the "Side effects explained" section above.

    Other warnings

    Eliquis may not be right for you if you have certain medical conditions. These are known as drug-condition interactions. Other factors may also affect whether Eliquis is a good treatment option for you.

    Talk with your doctor about your health history before starting Eliquis. The list below includes factors to consider.

    Artificial heart valve. It's not known whether it's safe for people with an artificial heart valve to take Eliquis. If you have an artificial heart valve, your doctor will likely not prescribe Eliquis. They'll recommend a different medication to take for treating or preventing blood clots.

    Upcoming surgical or dental procedures. Tell your doctor if you have any upcoming surgeries or dental procedures while you're taking Eliquis. This medication is a blood thinner and increases your risk of bleeding. Due to this risk, your doctor may recommend stopping Eliquis at a certain time before your procedure to prevent bleeding. It's recommended that you do not stop taking Eliquis without first talking with your doctor. They can determine the best treatment plan for you.

    Bleeding disorders. This medication can increase your risk of bleeding. If you have a bleeding disorder, you may have a higher risk of bleeding with Eliquis. Before you start taking this drug, tell your doctor about any bleeding disorder you have. This can help them determine whether it's safe for you to take Eliquis with your condition.

    Allergic reaction. If you've had an allergic reaction to Eliquis or any of its ingredients, your doctor will likely not prescribe Eliquis. Ask them what other medications are better options for you.

    Triple-positive antiphospholipid syndrome (APS). People with triple-positive APS may have an increased risk of blood clots from Eliquis. Before starting Eliquis treatment, tell your doctor if you have triple-positive APS. They'll likely recommend a medication other than Eliquis for your condition.

    Kidney problems. If you have kidney problems, tell your doctor before starting Eliquis. If your kidneys aren't working properly, this medication can build up in your body. Having too much Eliquis in your body may increase your risk of side effects. If you have kidney problems, your doctor may recommend a lower dose of Eliquis for you. Talk with your doctor about the best treatment plan for you.

    Liver problems. Eliquis can build up in your body if your liver isn't working properly. Having too much Eliquis in your body may increase your risk of side effects. If you have liver problems, tell your doctor before you start taking this drug. This will help them determine if Eliquis may be a safe treatment option for you. In some cases, they may recommend a different medication.

    Active bleeding. If you have any active bleeding, your doctor will not recommend that you start taking Eliquis. This medication can increase your risk of bleeding and may make active bleeding worse. Your doctor will recommend treating the bleeding before you start treatment with Eliquis.

    Alcohol and Eliquis

    There aren't any known interactions between Eliquis and alcohol.

    But alcohol can increase your risk of bleeding. Since Eliquis can also cause bleeding, drinking alcohol while taking Eliquis may further increase your risk of bleeding.

    If you drink alcohol, talk with your doctor about how much, if any, may be safe to consume while you're taking Eliquis.

    Pregnancy and breastfeeding while taking Eliquis

    It's not known if it may be safe to take Eliquis during pregnancy or while breastfeeding.

    At this time, there's not enough information to know whether Eliquis may cause harm to a developing fetus. But it's possible that taking Eliquis during pregnancy may increase the risk of bleeding. So Eliquis is currently not recommended for use during pregnancy.

    If you're taking Eliquis and need an epidural injection for pain relief during labor, you may have an increased risk of developing a spinal blood clot. Eliquis has a boxed warning for this risk. Boxed warnings are the most serious warnings from the Food and Drug Administration (FDA). They alert doctors and patients about drug effects that may be dangerous. For more information, see the "Side effects explained" section above.

    It's not known if Eliquis may be present in breast milk, or if it may affect a child who is breastfed. Because it's not known if breastfeeding is safe while taking Eliquis, it's currently not recommended.

    If you're pregnant or breastfeeding, or planning to become pregnant or breastfeed, talk with your doctor. They'll discuss whether Eliquis may be a safe treatment option for you.

    You may experience side effects during your treatment with Eliquis. Most of the drug's side effects are mild. But it's also possible to have serious side effects from this medication.

    Before you start treatment with Eliquis, talk with your doctor about the possible side effects of this medication. Here are some questions to help get you started:

  • What should I do if I become pregnant during Eliquis treatment?
  • Is my risk of side effects increased due to other medications that I'm taking?
  • How do the side effects of Eliquis compare with side effects of other medications used for my condition?
  • Is my risk of bleeding higher when I first start Eliquis?
  • To learn more about Eliquis, see these articles:

    To get information on different conditions and tips for improving your health, subscribe to any of Healthline's newsletters. You may also want to check out the online communities at Bezzy. It's a place where people with certain conditions can find support and connect with others.

    Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.


    Trodelvy Side Effects: What You Should Know

    Trodelvy (sacituzumab govitecan-hziy) is a brand-name injection for IV infusion that's prescribed for treating certain cancers in adults. As with other drugs, Trodelvy can cause side effects, such as diarrhea, hair loss, and low levels of certain blood cells.

    Trodelvy is used to treat the following types of cancer in certain situations:

    To use Trodelvy, the cancer must be locally advanced (spread to lymph nodes or nearby areas) or metastatic. Doctors typically prescribe the drug to people who have already tried other specific therapies for these cancers.

    Trodelvy is a biologic and belongs to a drug class called antibody-drug conjugates. The drug is not available in a biosimilar version.

    Read on to learn about potential common, mild, and serious side effects of Trodelvy. For a general overview of the drug, including details about its uses, see this article.

    Trodelvy can cause certain side effects, some of which are more common than others. These side effects may be temporary, lasting a few days to weeks. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.

    These are just a few of the more common side effects reported by people who took Trodelvy in clinical trials:

    * Trodelvy has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA).† For more information about this side effect, see the "Side effect specifics" section below.

    Mild side effects can occur with Trodelvy use. This list doesn't include all possible mild side effects of the drug. For more information, you can refer to Trodelvy's prescribing information.

    Mild side effects that have been reported with Trodelvy include:

    These side effects may be temporary, lasting a few days to weeks. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist.

    Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. If you develop a side effect while taking Trodelvy and want to tell the FDA about it, visit MedWatch.

    * Trodelvy has a boxed warning for this side effect. This is a serious warning from the FDA.† For more information about this side effect, see the "Side effect specifics" section below.

    Trodelvy may cause serious side effects. The list below may not include all possible serious side effects of the drug. For more information, you can refer to Trodelvy's prescribing information.

    If you develop serious side effects while taking Trodelvy, call your doctor right away. If the side effects seem life threatening or you think you're having a medical emergency, immediately call 911 or your local emergency number.

    Serious side effects that have been reported and their symptoms include:

    * Trodelvy has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA).† For more information about this side effect, see the "Side effect specifics" section below.

    Learn more about some of the side effects that Trodelvy may cause. To find out how often side effects occurred in clinical trials, see the prescribing information for Trodelvy.

    Diarrhea

    Some people may experience diarrhea from Trodelvy treatment. The drug has a boxed warning for the risk of severe diarrhea. Boxed warnings are the most serious warnings recommended by the FDA. The purpose of a boxed warning is to make patients and doctors aware of the risk of taking a medication.

    Diarrhea was a very common side effect that the majority of people taking Trodelvy reported in clinical trials. In most cases, diarrhea was mild, but in some cases, diarrhea was severe.

    Diarrhea may also be a symptom of an infection. Your doctor can determine what's causing your diarrhea. And they'll recommend the best way to treat it.

    What you can do

    While you're taking Trodelvy, your doctor will monitor you for diarrhea. If you get diarrhea, you should tell your doctor whether:

  • it's the first time you experience diarrhea with Trodelvy treatment
  • your diarrhea is black or bloody
  • your diarrhea does not slow down within 24 hours
  • you have symptoms of dehydration, such as dizziness
  • you're vomiting or too nauseous to drink any fluids
  • If you have diarrhea, your doctor may recommend taking an antidiarrheal medication to help decrease this side effect. To help prevent diarrhea, they may also give you another drug, such as atropine, before your Trodelvy dose.

    It's possible for diarrhea, especially severe diarrhea, to cause dehydration. So it's recommended that you stay hydrated throughout your Trodelvy treatment. In severe cases, your doctor may prescribe certain fluids or electrolytes to help you stay hydrated.

    If you have severe diarrhea, your doctor may recommend a lower dose of Trodelvy. (To learn about the dosage of Trodelvy, see this article.) Or they may recommend you stop Trodelvy treatment. They might also prescribe a different medication for your condition.

    Low levels of certain white blood cells

    It's possible to develop low levels of certain white blood cells from taking Trodelvy. In fact, this medication has a boxed warning for this risk. Boxed warnings are the most serious warnings recommended by the FDA. The purpose of a boxed warning is to be sure that patients and doctors are aware of the risk of taking a medication.

    Specifically, Trodelvy can decrease the levels of white blood cells called neutrophils. These cells are a part of your immune system, and they help your body fight infection. Low neutrophil levels can increase the risk of infection, which can become serious. This side effect was common in people taking Trodelvy in clinical trials, and in some cases it was severe.

    If you develop low neutrophil levels, you usually won't have symptoms. However, if your neutrophil levels get too low, you may have an increased risk of infection. So, it's important to be aware of the symptoms of infection.

    Symptoms can include:

  • fever or chills
  • shortness of breath
  • burning or pain while urinating
  • cough
  • Though rare, some people with low neutrophil levels developed a condition called febrile neutropenia. With febrile neutropenia, your neutrophil levels are very low and you have a fever. It can also be life threatening.

    What you can do

    Be sure to report any symptoms of infection to your doctor immediately. If you develop an infection or febrile neutropenia, your doctor will recommend treatment with antibiotics right away.

    Throughout your Trodelvy treatment, your doctor will monitor your white blood cell levels. If they become too low, your doctor may recommend decreasing your Trodelvy dose. (To learn about the dosage of Trodelvy, see this article.) In some cases, your doctor may recommend taking another drug to increase your neutrophil levels.

    If your neutrophils do not return to their usual levels after a few weeks, your doctor may recommend a different medication for your cancer.

    Hair loss

    Some people may experience hair loss from taking Trodelvy. Hair loss was a common side effect that people taking Trodelvy reported in clinical trials.

    What you can do

    If you experience hair loss during your treatment with Trodelvy, talk with your doctor. If it's severe or bothersome to you, your doctor may recommend ways to decrease this side effect. For example, they may recommend using an over-the-counter drug, such as Rogaine (minoxidil), to help decrease hair loss.

    Infusion-related reactions

    Infusion-related reactions are possible from Trodelvy treatment.* These reactions may occur during your IV infusion or within 24 hours of your dose. Infusion-related reactions were not very common in clinical trials.

    Symptoms can include:

    * Trodelvy is given by IV infusion. For more information, see this article.

    What you can do

    You should be aware of the above symptoms of an infusion-related reaction. This is so you can tell your doctor right away if you develop symptoms.

    After your dose of Trodelvy has been completed, your doctor will monitor you for 30 minutes. This is to watch for any infusion-related reactions that may occur.

    If you develop an infusion-related reaction while you're receiving your dose of Trodelvy, your doctor may recommend slowing down your infusion. This may help decrease the symptoms of the reaction. If your reaction does not improve or is severe, your doctor may recommend stopping your infusion.

    Before your next infusion, your doctor will give you certain medications to help prevent infusion-related reactions. These may include Tylenol (acetaminophen) or Benadryl (diphenhydramine).

    If you develop symptoms of an infusion-related reaction after you leave your doctor's office or infusion center, call your doctor or go to a hospital right away.

    Allergic reaction

    As with most drugs, Trodelvy can cause an allergic reaction in some people. This side effect occurred in some people taking Trodelvy in clinical trials. In rare cases, allergic reactions may be severe or life threatening.

    Symptoms can be mild or serious and can include:

  • skin rash
  • itching
  • flushing
  • swelling under your skin, typically in your eyelids, lips, hands, or feet
  • swelling of your mouth, tongue, or throat, which can make it hard to breathe
  • What you can do

    For mild symptoms of an allergic reaction, call your doctor right away. They may recommend ways to ease your symptoms and determine whether you should keep taking Trodelvy. But if your symptoms are serious and you think you're having a medical emergency, immediately call 911 or your local emergency number.

    Trodelvy may cause several side effects. Here are some frequently asked questions about the drug's side effects and their answers.

    Can Trodelvy cause any long-term side effects?

    Yes, it's possible for Trodelvy to cause long-term side effects, such as kidney problems.*

    However, most side effects that people taking this medication experienced were short term. Or they went away after stopping Trodelvy treatment.

    If you're concerned about developing long-term side effects during your Trodelvy treatment, talk with your doctor. They can discuss the risk of side effects with you.

    * To learn more about this side effect, see the "Serious side effects of Trodelvy" section above.

    If I have side effects from Trodelvy, when should I call my doctor?

    Tell your doctor about any side effects that you have from Trodelvy treatment. If you have side effects that are severe or bothersome to you, tell your doctor right away.

    It's important to call your doctor if you experience symptoms of:

    Your doctor can help determine whether your side effects are severe. They can also treat these side effects right away so that they don't worsen. In some cases, they may recommend other medications to help prevent these side effects from occurring.

    Your doctor can also advise whether you'll need to change your treatment plan due to these side effects. If you have severe side effects or an allergic reaction to Trodelvy, your doctor will likely recommend a different treatment option for your cancer.

    Be sure to tell your doctor if you have any side effects from Trodelvy treatment.

    * To learn more about this side effect, see the "Serious side effects of Trodelvy" section above.† For more information about this side effect, see the "Side effect specifics" section above.‡ Trodelvy has a boxed warning for this side effect. This is a serious warning from the Food and Drug Administration (FDA).

    Tell your doctor about any medical conditions or medications that you're taking. In some cases, Trodelvy may not be the best treatment option for you. Your doctor can help determine whether Trodelvy is a safe medication for you to take.

    Boxed warnings

    This drug has boxed warnings about the risks of diarrhea and low levels of certain white blood cells. These are serious warnings from the Food and Drug Administration (FDA). For details, see the "Side effect specifics" section above.

    Other precautions

    Be sure to talk with your doctor about your health history before you take Trodelvy. This drug may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. The conditions and factors to consider include:

    Low UGT1A1 activity. If you have a decrease in the activity of a specific gene called UGT1A1, you may have an increased risk of developing low levels of certain white blood cells from Trodelvy. And this can be severe. You may also have an increased risk of low red blood cell levels. In this case, your doctor may monitor your blood cell levels more often during treatment. If there are changes to your blood cell levels, your doctor may recommend a lower dose* of Trodelvy. Or they may recommend you stop Trodelvy treatment.

    Allergic reaction. If you've had an allergic reaction to Trodelvy or any of its ingredients, your doctor will likely not prescribe the drug. Ask your doctor what other medications may be better options for you.

    Liver problems. It's not known if Trodelvy treatment is safe for people with moderate to severe liver problems. This medication has not been studied in people with certain liver problems. If you have any liver problems, tell your doctor before taking Trodelvy. They can determine whether this drug may be a safe treatment option for you. Or they may recommend a different medication for your cancer.

    * To learn about the dosage of Trodelvy, see this article.

    Alcohol and Trodelvy

    There are no known interactions between Trodelvy and alcohol.

    However, it's possible for alcohol to worsen certain side effects from Trodelvy treatment. For example, both Trodelvy and alcohol may increase the risk of:

  • nausea
  • vomiting
  • headache
  • dizziness
  • If you'd like to drink alcohol during your treatment with Trodelvy, talk with your doctor about how much, if any, is safe for you.

    Pregnancy and breastfeeding while taking Trodelvy

    Trodelvy is not safe to receive during pregnancy or while breastfeeding.

    Currently, there haven't been any studies done in pregnant people to see what effects the drug may have on a developing fetus. However, due to the way this drug works to treat cancer, Trodelvy may cause pregnancy loss or congenital anomalies (commonly known as birth defects).

    Due to this risk, your doctor will recommend you use birth control during Trodelvy treatment. And they'll recommend this for at least 6 months after stopping treatment.

    Also, if you're male,* you should use birth control if you have partners who can become pregnant. You should also use it for at least 3 months after your Trodelvy treatment ends.

    It's not known whether Trodelvy passes into breast milk or what effects it may have on a child who's breastfed.

    However, due to any possible risks to your child, your doctor will not recommend breastfeeding during Trodelvy treatment. And they will not recommend breastfeeding for at least 1 month after the end of your treatment.

    * Sex and gender exist on spectrums. Use of the term "male" in this article refers to sex assigned at birth.

    It's possible to experience side effects during your treatment with Trodelvy. Most side effects are mild, but some side effects of Trodelvy may be severe. You should be aware of possible side effects that may occur and when to see your doctor.

    If you'd like to learn more about Trodelvy, talk with your doctor or pharmacist. They can help answer any questions you have about side effects from taking the drug.

    Besides talking with your doctor, you can do some research on your own. These articles might help:

  • More information about Trodelvy. For details about other aspects of Trodelvy, refer to this article.
  • Dosage details. For information about Trodelvy's dosage, see this article.
  • A look at your condition.
  • Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.






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