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Side Effect(s) Of Doxepin
Review the side-effects of Doxepin as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist. Anticholinergic Effects - Dry mouth, blurred vision, constipation and urinary retention. Central Nervous System - Drowsiness, confusion, disorientation, hallucinations, numbness, tingling, incoordination, seizures, tardive dyskinesia and tremor. Heart - Low/high blood pressure and fast heart rate. Allergic - Skin rash, swelling in the face, lips, eyes, mouth, light sensitivity and itching. Blood - Eosinophilia, bone marrow depression and bruising. Gastrointestinal - Nausea, vomiting, indigestion, taste disturbances, diarrhea and loss of appetite. Genitourinary - Raised or lowered sexual drive, testicular swelling, breast enlargement in males, spontaneous milk secretion in females and raising or lowering of blood sugar levels. Miscellaneous - Dizziness, ringing in the ear, weight gain, increased sweating, chills, fatigue, weakness, flushing, jaundice, hair loss, headache and fever. Other Precautions : Avoid excess dosage. Drug Name : Doxepin Doxepin(Adapin) generic is an antidepressant, prescribed for depression. It blocks the activity of acetylcholine and histamine and affects the action of serotonin and norepinephrine. More info about DoxepinTrade Names for Doxepin India : MoreInternational : Adapin, SilenorSide Effects Of Biktarvy: What You Need To Know
Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) is a prescription drug that's used to treat HIV in adults and some children. Biktarvy can cause side effects that range from mild to serious. Examples include fatigue and skin rash.
Some people may experience mild to serious side effects during treatment with Biktarvy. Listed below are some examples of the drug's commonly reported side effects. But these are not all the possible side effects of Biktarvy.
Some common side effects include:
These are just a few of the more common side effects reported by people in studies of Biktarvy.
Biktarvy may cause some mild side effects.
Examples that have been reported with this drug include:
* To learn more about this side effect, see the "Side effects explained" section below.
In most cases, these side effects should be temporary. And some may be easily managed. But if you have symptoms that are ongoing or bother you, talk with your doctor or pharmacist. And do not stop taking Biktarvy unless your doctor recommends it.
Biktarvy may cause mild side effects other than those listed above. See the drug's prescribing information for details.
Biktarvy may cause serious side effects, but they're usually less common than mild ones.
Serious side effects that have been reported with Biktarvy include:
If you develop serious side effects while taking Biktarvy, call your doctor right away. If the side effects seem life threatening or you think you're having a medical emergency, immediately call 911 or your local emergency number.
* To learn more, see the "Side effects explained" section below.† Biktarvy has a boxed warning for this side effect. This is the most serious warning from the Food and Drug Administration (FDA). To learn more, see the "Side effects explained" section below.
Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. If you'd like to notify the FDA about a side effect you've had with Biktarvy, visit MedWatch.
Get answers below to some frequently asked questions about Biktarvy's side effects.
Does Biktarvy cause weight gain?It's possible. Weight gain wasn't reported in studies of Biktarvy, but it has been reported since Biktarvy and similar drugs were approved for use. Biktarvy contains the active ingredients bictegravir (BIC), emtricitabine (FTC), and tenofovir alafenamide (TAF).
BIC belongs to a group of drugs called integrase strand transfer inhibitors (INSTIs). FTC and TAF belong to a group of drugs called nucleoside reverse transcriptase inhibitors (NRTIs).
It's possible for both INSTIs and NRTIs to cause weight gain in some cases.
If you experience weight gain during treatment with Biktarvy, talk with your doctor. They'll help determine whether Biktarvy is the cause. They can also suggest ways to manage your weight while taking this drug.
Are there any long-term side effects of Biktarvy?Yes. Biktarvy may cause long-term side effects, but they're not common.
Long-term side effects include:
* To learn more, see the "Side effects explained" section below.† Biktarvy has a boxed warning for this side effect. This is the most serious warning from the Food and Drug Administration (FDA). To learn more, see the "Side effects explained" section below.
Long-term side effects may begin during treatment with Biktarvy. And in some cases, they may continue after treatment ends.
If you have ongoing side effects while taking Biktarvy, talk with your doctor. They'll determine whether you need to stop taking it and switch to a different HIV medication instead.
Do not stop taking Biktarvy without first talking with your doctor. Suddenly stopping this drug can cause serious side effects if you have certain conditions. (See "Side effects explained" below for more information.)
Your doctor will monitor you for worsening of certain conditions if you stop taking Biktarvy.
Does Biktarvy cause neuropathy?No, neuropathy (nerve damage) wasn't reported in studies of the drug. Some symptoms of neuropathy include:
If you experience symptoms of neuropathy, talk with your doctor. They'll discuss possible causes with you and suggest ways to help manage your symptoms.
Will I have hair loss from Biktarvy?No, this wasn't a side effect reported in studies of the drug.
But Biktarvy contains the active ingredients emtricitabine and tenofovir alafenamide. These belong to a group of drugs called NRTIs. And there have been reports of hair loss with NRTIs.
If you have hair loss while taking Biktarvy, talk with your doctor. They'll suggest ways to help manage this side effect.
Learn more about some of the side effects Biktarvy may cause.
Risk of worsening hepatitis BBiktarvy has a boxed warning for the risk of worsening hepatitis B. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).
Biktarvy may lead to a worsening of hepatitis B in some people. You have an increased risk of worsening hepatitis B infection if you also have HIV and stop taking Biktarvy.
If you have both conditions, your doctor will monitor your liver function for several months if you stop taking Biktarvy. This is to make sure the hepatitis B infection isn't becoming worse. If it is, you may need treatment for it.
For more details on this serious side effect, see the prescribing information or talk with your doctor or pharmacist.
What might helpYour doctor will check whether you have hepatitis B infection before you begin treatment with Biktarvy. Do not suddenly stop taking Biktarvy if you have both HIV and hepatitis B. This could increase your risk of serious liver damage from worsening hepatitis B.
If you have both infections and need to stop taking Biktarvy, your doctor will monitor your liver function for several months after you stop treatment. This is to make sure the hepatitis B infection isn't worsening.
You may need treatment for hepatitis B infection if your condition worsens after you stop Biktarvy.
Skin rashBiktarvy may cause a skin rash in some people. But this wasn't very common in the drug's studies.
What might helpIf you develop a rash while taking Biktarvy, tell your doctor. If it's a mild rash, they may recommend an antihistamine such as diphenhydramine (Benadryl). They may also recommend hydrocortisone cream, which you apply to the affected areas of your skin.
But if you have a severe rash, this may be a sign of an allergic reaction to Biktarvy. You should call 911 or go to an emergency medical center immediately if you have this or other symptoms of a severe allergic reaction. These include trouble breathing and swelling under your skin or in your mouth or throat. (See "Allergic reaction" above for more information.)
New or worsening kidney problemsBiktarvy can cause new or worsening kidney problems, including kidney failure in some people. Taking certain other drugs that also affect your kidneys may increase your risk of kidney problems from Biktarvy. Tell your doctor about all the medications you take and whether you have a history of kidney disease.
Symptoms of kidney problems include issues with urination, such as:
What might helpYour doctor will check your kidney function before you start Biktarvy and will monitor it throughout your treatment. If you develop signs of kidney problems, they'll determine whether this drug is right for you based on the severity of your symptoms. In some cases, they'll have you stop Biktarvy and will recommend an alternative that's safer for you.
Lactic acidosisBiktarvy may cause a serious reaction known as lactic acidosis. This is when your body has too much lactic acid and can't get rid of it. This can be life threatening in certain cases.
Symptoms of lactic acidosis include:
What might helpTell your doctor if you have liver or kidney problems. These organs remove Biktarvy from your body. If they're not functioning properly, lactic acid can build up in your system. This can increase your risk of developing lactic acidosis.
Your doctor will monitor your liver and kidney function before you start Biktarvy and during your treatment. But if you experience symptoms of lactic acidosis, call 911 or your local emergency number immediately.
Keeping track of side effects
During your Biktarvy treatment, consider taking notes on any side effects you're having. You can then share this information with your doctor. This is especially helpful when you first start taking new drugs or using a combination of treatments.
Your side effect notes can include things such as:
Keeping notes and sharing them with your doctor will help them learn more about how Biktarvy affects you. They can then use this information to adjust your treatment plan if needed.
Below are several warnings about Biktarvy. This drug may not be suitable for you in certain situations. Your doctor will determine whether it's the right treatment option for you based on your health.
Boxed warning: Risk of worsening hepatitis BBiktarvy has a boxed warning for the risk of worsening hepatitis B. A boxed warning is the most serious warning from the Food and Drug Administration (FDA).
To learn more, see the "Side effects explained" section above.
Other warningsBiktarvy can sometimes cause harmful effects in people who have certain conditions. This is known as a drug-condition interaction. Other factors may also affect whether Biktarvy is a good treatment option for you.
Talk with your doctor about your health history before you take Biktarvy. Be sure to tell them if any of the following factors apply to you:
Biktarvy is a prescription drug used to treat HIV. It can cause mild to serious side effects. Reactions to this drug can vary depending on your age, other medical conditions you may have, and other medications you take.
If you have questions about side effects from Biktarvy, ask your doctor for more information. Here are some questions to get you started:
To learn more about Biktarvy, see these articles:
To get information on different conditions and tips for improving your health, subscribe to any of Healthline's newsletters. You may also want to check out the online communities at Bezzy. It's a place where people with certain conditions can find support and connect with others.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
Side Effects Of Keytruda: Examples And Treatment
Keytruda (pembrolizumab) is a prescription drug that's used to treat certain kinds of cancer. It can cause side effects that range from mild to serious. Examples of side effects Keytruda can cause include fatigue, rash, and muscle or bone pain.
Keytruda is used to treat many kinds of cancer in adults and certain children. Examples of some of these cancers include certain forms of:
Keytruda is a biologic drug. Its active ingredient is pembrolizumab. (An active ingredient is what makes a drug work.) The drug comes as a liquid solution a healthcare professional injects into a vein over a period of time. This is called an intravenous (IV) infusion.
Keep reading to learn about the common, mild, and serious side effects that Keytruda can cause. For a general overview of the drug, including details about all of the cancers Keytruda treats, see this article.
Some people may experience mild or serious side effects during their Keytruda treatment. These side effects can vary depending on whether Keytruda is used alone or with other cancer drugs.
Examples of Keytruda's commonly reported side effects include:
* To learn more about this side effect, see "Side effects explained" below.
Read on to learn about other possible side effects of Keytruda.
Keytruda may cause mild side effects. These side effects can vary depending on whether Keytruda is used alone or with other cancer drugs.
Examples of mild side effects that have been reported with Keytruda include:
* To learn more about this side effect, see "Side effects explained" below.
In most cases, these side effects should be temporary. And some may be easily managed, too. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. And don't stop receiving Keytruda unless your doctor tells you to.
Keytruda may cause mild side effects other than the ones listed above. See the Keytruda prescribing information for more details.
Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. If you'd like to notify the FDA about a side effect you've had with Keytruda, visit MedWatch.
Serious side effects may occur with Keytruda. These side effects can vary depending on whether Keytruda is used alone or with other cancer drugs.
Many of Keytruda's serious side effects happen because of an overactive immune system. These are called immune-mediated side effects, and they often cause inflammation (damage and swelling) to tissues. Examples include:
Other serious side effects that have been reported with Keytruda include:
* To learn more about this side effect, see "Side effects explained" below.
If you develop serious side effects during Keytruda treatment, contact your doctor right away. If the side effects seem life threatening or if you think you're having a medical emergency, immediately call 911 or your local emergency number.
Get answers to some frequently asked questions about Keytruda's side effects.
Does Keytruda cause any long-term side effects?In most cases, Keytruda's side effects should be temporary. Most should go away soon after you start or stop the drug.
But Keytruda can cause serious side effects that may lead to long-term problems. In some cases, these problems can take many weeks or months to resolve. Here are some examples, all of which cause inflammation (damage and swelling) in different parts of the body:
These are not all the long-term side effects that Keytruda may cause. If you have questions about what to expect long term while receiving Keytruda, talk with your doctor or pharmacist. But don't stop your Keytruda treatment unless your doctor recommends it.
When do Keytruda side effects usually start?It's hard to say. Keytruda side effects can happen any time after you start receiving this drug. Some may even occur after you stop Keytruda treatment.
When you start Keytruda, a healthcare professional will give you the drug as an intravenous (IV) infusion. You may have side effects called infusion reactions from this procedure. Examples of infusion reactions include fever, chills, low blood pressure, and low levels of oxygen in the blood. Sometimes, infusion reactions can be severe.
A healthcare professional will monitor you for infusion reactions while you're receiving doses of the drug.
When you might develop side effects may also depend on whether you receive Keytruda alone or in combination with other drugs. Having certain risk factors might also affect the timing of side effects occurring. (For more information, see the "Warnings for Keytruda" section below.)
Your doctor can tell you more about what to expect regarding when certain side effects might happen.
Could I experience any eye problems while using Keytruda?Yes, in rare cases, Keytruda may cause serious eye side effects (sometimes called ocular side effects).
Examples of eye problems that may happen while receiving Keytruda include:
Symptoms of eye side effects from Keytruda will depend on the exact eye problem you have. But possible symptoms that may happen with one or both eyes include:
Tell your doctor right away if you have any symptoms of eye problems while receiving Keytruda.
What are Keytruda's side effects when it's used to treat lung cancer?Keytruda is prescribed to treat many types of cancer, including non-small cell lung cancer. The side effects of Keytruda are expected to be the same regardless of the type of cancer it's treating.
However, Keytruda may be prescribed by itself or with other drugs for lung cancer, such as chemotherapy drugs. This can affect the side effects you experience.
In addition to the side effects Keytruda may cause when given alone, the following side effects also occurred when Keytruda was given with chemotherapy in studies:
For a list of the cancers Keytruda is used to treat, see this in-depth article on the drug.
To learn more about possible side effects of Keytruda, see the "What are the mild side effects of Keytruda?" and "What are the serious side effects of Keytruda?" sections above.
If you have questions about what to expect when receiving Keytruda to treat lung cancer, talk with your doctor.
Is confusion a side effect of Keytruda?Yes, confusion is a possible side effect of Keytruda. In fact, confusion was a common side effect of Keytruda in studies of the drug.
Confusion can make you feel as though you can't think clearly. You may also have problems making decisions or focusing on a task. This side effect can also lead to atypical or slurred speech.
It's important to remember that encephalitis (inflammation of your brain) may cause confusion. Encephalitis is a rare but serious side effect of Keytruda. For this reason, you should tell your doctor right away if you experience confusion while receiving Keytruda. They'll likely check you for signs of encephalitis.
Learn more about some of the side effects Keytruda may cause.
Muscle or bone painMuscle pain or bone pain are common side effects of Keytruda.
What might helpYou can relieve muscle or bone pain by:
Before taking OTC drugs with Keytruda, talk with your doctor or pharmacist. Also ask your doctor about other ways to relieve bothersome muscle or bone pain that Keytruda may cause.
Hair lossIn rare cases, some people may have hair loss while receiving Keytruda. In studies, hair loss was more common when Keytruda was used with chemotherapy drugs than when used alone.
What might helpHair loss as a side effect of Keytruda is usually temporary. If you have hair loss from receiving Keytruda, your hair should start growing back several weeks after your last dose.
Cooling caps, which are caps designed to keep your scalp cold, might help prevent hair loss. Cooling caps lessen the blood flow to your scalp, which may decrease the effect of Keytruda or chemotherapy on your hair. Ask your doctor if a cooling cap is right for you.
When your hair does start to return, don't overuse hair styling tools that are harsh on hair. These include blow dryers and hair straighteners. You should also avoid bleaching or coloring your hair so it stays healthy enough to grow.
If you experience bothersome hair loss during Keytruda treatment, talk with your doctor about ways to help with this side effect.
Itchy skin or rashYou may have itchy skin or rash from receiving Keytruda. Itchy skin and mild rashes are common side effects of the drug.
In rare cases, Keytruda may also cause severe rashes and other skin reactions. These include Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). With SJS and TEN, you have a rash along with painful sores on your eyes, genitals, mouth, or throat. These reactions are potentially life threatening and require immediate medical attention.
What might helpHere are a few tips for helping relieve mild itching and rash:
If you have a severe skin reaction to Keytruda, you'll likely need treatment in a hospital. If you have severe skin peeling or blisters after receiving the drug, call 911 or your local emergency number right away. These may be signs of a serious skin reaction, which can be life threatening.
If you're concerned about your risk of a severe skin reaction from Keytruda, talk with your doctor.
Allergic reactionLike most drugs, Keytruda can cause an allergic reaction in some people.
Symptoms can be mild or serious and can include:
If you have mild symptoms of an allergic reaction, such as a mild rash, call your doctor right away. They may suggest an over-the-counter antihistamine you can take by mouth, such as diphenhydramine (Benadryl), or a product you can apply to your skin, such as hydrocortisone cream, to manage your symptoms.
If your doctor confirms you had a mild allergic reaction to Keytruda, they'll decide whether you should continue receiving it.
If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. These symptoms could be life threatening and require immediate medical care.
If your doctor confirms you had a serious allergic reaction to Keytruda, they may have you switch to a different treatment.
Keeping track of side effects
During your Keytruda treatment, consider keeping notes on any side effects you're having. Then, you can share this information with your doctor. This is especially helpful to do when you first start taking new drugs or using a combination of treatments.
Your side effect notes can include things like:
Keeping notes and sharing them with your doctor will help your doctor learn more about how Keytruda affects you. And your doctor can use this information to adjust your treatment plan if needed.
Keytruda is used to treat certain types of cancer in some children. (For information about the cancers Keytruda can treat in children, see this detailed article on the drug.)
Most side effects that occur in children receiving Keytruda are similar to those that adults experience. However, some side effects of Keytruda are more common in children. These include:
Talk with your child's doctor about their risk of side effects from Keytruda.
Keytruda may not be right for you if you have certain medical conditions or other factors that affect your health. Talk with your doctor about your health history before you start Keytruda. Factors to consider include those in the list below.
Allergic reaction: If you've had an allergic reaction to Keytruda or any of its ingredients, you shouldn't receive Keytruda. Ask your doctor what other medications are better options for you.
Receiving certain other treatments for multiple myeloma: Using Keytruda with certain other treatments for multiple myeloma can be fatal. (Multiple myeloma is a cancer that affects a type of white blood cell called a plasma cell.) Before starting Keytruda, tell your doctor if you're taking any treatments for multiple myeloma.
Received an organ transplant: Before starting Keytruda, tell your doctor if you've had an organ transplant. Keytruda can raise the risk of your immune system attacking the transplanted organ. If you've had a transplant, your doctor will tell you what symptoms of organ rejection you should watch for while receiving Keytruda.
Received or plan to receive a stem cell transplant: Before starting Keytruda, tell your doctor if you've received stem cells from a donor in the past or plan to do so. You may be at a higher risk of graft-versus-host disease. This condition causes your immune system to attack the transplant stem cells. Talk with your doctor about whether Keytruda is safe for you to use.
Alcohol and KeytrudaIt should be safe to drink alcohol while receiving Keytruda.
But be aware that alcohol can cause side effects that are similar to some of Keytruda's. These include diarrhea, fatigue, and nausea. If you drink alcohol during Keytruda treatment, it may make these side effects worse.
If you drink alcohol, talk with your doctor about the amount that's safe for you to drink while receiving Keytruda.
Pregnancy and breastfeeding while receiving KeytrudaYou shouldn't use Keytruda while pregnant or breastfeeding.
Keytruda hasn't been studied during pregnancy. But based on how the drug works, Keytruda may cause harm to infants born to females* who used the drug during pregnancy.
For this reason, you should use birth control during Keytruda treatment if you or your partner can become pregnant. And you should continue to use birth control for at least 4 months after your last dose.
It isn't known whether Keytruda can pass into breast milk. To be safe, you shouldn't breastfeed while receiving Keytruda and for at least 4 months after your last dose.
Before starting Keytruda treatment, tell your doctor if you're pregnant or planning to become pregnant. Also tell them if you're breastfeeding or planning to breastfeed. They can discuss your options with you.
* In this article, we use the term "female" to refer to someone's sex assigned at birth. For information about the difference between sex and gender, see this article.
Keytruda is a drug used to treat certain types of cancer in adults and some children.
Some people who use Keytruda may have mild side effects. Although rare, serious side effects can occur with Keytruda. Many of these happen because of an overactive immune system. Keep in mind that the side effects of Keytruda can vary depending on whether Keytruda is used alone or with other cancer drugs.
Talk with your doctor or pharmacist if you have questions about Keytruda's side effects. Here are a few questions you may want to ask:
To learn more about Keytruda, see these articles:
To get information on different conditions and tips for improving your health, subscribe to any of Healthline's newsletters. You may also want to check out the online communities at Bezzy. It's a place where people with certain conditions can find support and connect with others.
Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.
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