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Seroquel And Cost

Seroquel (quetiapine) is a brand-name drug prescribed for schizophrenia and certain other mental health conditions. The cost of Seroquel, with and without insurance, can depend on several factors.

Seroquel comes in two forms: Seroquel oral tablets and Seroquel XR extended-release oral tablets.

With extended release, the drug is slowly released into your body over a long period of time. You may see Seroquel oral tablet labeled, "Seroquel immediate-release (IR) oral tablet." With immediate release, the drug is released into your body soon after taking your dose.

The term "Seroquel" in this article refers to both Seroquel (or Seroquel IR) and Seroquel XR unless specified.

Keep reading to learn about Seroquel and cost. For details about its uses and more, see the Seroquel overview article.

As with all medications, the cost of Seroquel can vary. Factors that may affect the price you'll pay include:

  • your treatment plan
  • your insurance coverage
  • the pharmacy you use
  • whether Seroquel has a savings program (see the "Financial and insurance assistance" section)
  • To find out what the cost of Seroquel will be for you, talk with your doctor, pharmacist, or insurance provider. Or look below in the next section to learn how much you can save by using an Optum Perks coupon.

    To save money on your Seroquel prescription, explore these Optum Perks coupons.

    The active ingredient of Seroquel is quetiapine. It's available as the generic drugs quetiapine oral tablet and quetiapine extended-release oral tablet. A generic drug is considered to be as safe and effective as the original drug. And generics tend to cost less than brand-name drugs.

    If your doctor has prescribed Seroquel and you're interested in taking the generic Seroquel instead, talk with your doctor. They may prefer one version or the other. You'll also need to check with your insurance provider, as it may cover only one or the other.

    To find out how the cost of this generic drug compares with the cost of Seroquel, talk with your doctor, pharmacist, or insurance provider.

    If you take Seroquel long term, you may be able to lower its cost in the following ways.

    Getting a 3-month supply

    You may be able to get a 90-day supply of Seroquel. If approved by your insurance company, getting a 90-day supply of the drug could reduce your number of trips to the pharmacy and help lower the cost. If you're interested in this option, check with your doctor, pharmacist, or insurance provider.

    Using a mail-order pharmacy

    Seroquel may be available through a mail-order pharmacy. Using this type of service may help lower the drug's cost and allow you to receive your medication without leaving home. Some Medicare plans may help cover the cost of mail-order medications. You may also be able to get a 90-day supply of the drug via mail order.

    If you don't have health insurance, talk with your doctor or pharmacist. They may be able to suggest online pharmacy options that could work for you.

    If you need financial support to pay for Seroquel, or if you need help understanding your insurance coverage, help is available. Some websites provide details about drug assistance programs, ways to make the most of your insurance coverage, and links to savings cards and other services. Two such websites are:

    Here are answers to some frequently asked questions about drug cost and Seroquel.

    What does Seroquel cost with insurance vs. Without it?

    What you pay for Seroquel if you have insurance compared with what you'd pay without it depends on several factors.

    Factors that could affect what you pay for this drug without insurance include:

  • the quantity you're prescribed (such as a 90-day or 30-day supply)
  • your Seroquel dosage and treatment plan
  • the pharmacy you use
  • the form of the drug you're prescribed (such as Seroquel or Seroquel XR)
  • These same factors may affect your price for Seroquel if you have insurance. But the price you pay with insurance will also depend on:

  • your specific plan benefits
  • any prior authorization requirements you have for drug coverage
  • To learn more about what you'd pay for Seroquel with or without insurance, talk with your doctor, pharmacist, or insurance provider (if you have one).

    You can also visit Optum Perks for price estimates of Seroquel and Seroquel XR when using coupons from their site. However, Optum Perks coupons cannot be used with insurance benefits or copays. (Optum Perks is a sister site of Medical News Today.)

    How does the cost of Seroquel vs. Seroquel XR compare?

    The price you'd pay for Seroquel may depend on the form you're prescribed and other factors. But the cost of these drugs is likely to be similar because they contain the same active ingredient. Other factors that may affect your prescription cost for Seroquel and Seroquel XR include:

  • the length of your treatment and the quantity you're prescribed
  • whether there are payment assistance programs for your prescribed treatment (see the "Financial and insurance assistance" section)
  • whether you're paying out of pocket or have insurance (see the question above for details)
  • To learn more about the cost of Seroquel versus Seroquel XR, talk with your doctor, pharmacist, or insurance provider.

    Note: Seroquel and Seroquel XR have similar uses but also some different ones. For example, both are approved to treat schizophrenia but only Seroquel XR is approved to treat major depressive disorder (also known as depression).

    Below is information you may want to consider if you have insurance and receive a prescription for Seroquel.

    If you have insurance, your insurance company may require prior authorization before it covers Seroquel. This means the company and your doctor will discuss Seroquel in regard to your treatment. The insurance company will then determine whether the medication is covered.

    If a drug requires prior authorization, but you start treatment without the prior approval, you could pay the full cost of the medication. You can ask your insurance company whether Seroquel requires prior authorization.

    Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses.


    Seroquel Xr

    Seroquel Xr Generic Name & Formulations General Description

    Quetiapine (as fumarate) 50mg, 150mg, 200mg, 300mg, 400mg; ext-rel tabs.

    Pharmacological Class

    Dibenzothiazepine.

    How Supplied

    XR—60; Tabs 25mg, 50mg, 100mg, 200mg, 400mg—100; 300mg—60

    Seroquel Xr Indications Indications

    Acute treatment of manic or mixed episodes in bipolar I disorder, as monotherapy and as an adjunct to lithium or divalproex. Depressive episodes associated with bipolar disorder in adults. Maintenance treatment of bipolar I disorder, as an adjunct to lithium or divalproex in adults. Adjunct to antidepressants for major depressive disorder (MDD) in adults.

    Seroquel Xr Dosage and Administration Adult

    Swallow whole. Take on an empty stomach or with light meal. Give once daily in the PM. Mania: 300mg on day 1, then 600mg on day 2, then titrate to effective dose beginning on day 3, usually 400–800mg/day. Maintenance: usual range 400–800mg/day. Depressive episodes due to bipolar disorder: 50mg on day 1, then 100mg on day 2, then 200mg on day 3, then 300mg on day 4; max 300mg/day. Adjunct to MDD: 50mg/day on days 1 and 2, then 150mg/day on day 3, then titrate to effective dose, usual range: 150–300mg/day. Elderly, debilitated, or risk of postural hypotension: titrate more slowly to lower target dose. Elderly or hepatic impairment: initially 50mg/day; may increase at increments of 50mg/day. Concomitant CYP3A4 inhibitors or inducers, reinitiation of treatment: see full labeling. Switching from Seroquel immediate-release: give XR at equivalent total daily dose taken once daily.

    Children

    Mania: <10yrs: not established. Swallow whole. Take on an empty stomach or with light meal. Give once daily in the PM. 10–17yrs: 50mg on day 1, then 100mg on day 2, then 200mg on day 3, then 300mg on day 4, then 400mg on day 5; may further increase up to target range of 400–600mg/day; max 600mg/day. Bipolar depression, maintenance: <18yrs: not established.

    Seroquel Xr Contraindications

    Not Applicable

    Seroquel Xr Boxed Warnings Boxed Warning

    Increased mortality in elderly patients with dementia-related psychosis. Suicidal thoughts and behaviors.

    Seroquel Xr Warnings/Precautions Warnings/Precautions

    Elderly with dementia-related psychosis (not approved use); increased risk of death or cerebrovascular events (eg, stroke, TIA). Increased risk of suicidal thoughts and behavior in children, adolescents, and young adults; monitor closely for worsening or unusual changes in all patients. Exclude neuroleptic malignant syndrome if fever or other symptoms occur. Diabetes. Monitor for hyperglycemia, hyperlipidemia: do fasting blood glucose and lipids testing initially and during therapy. Monitor for weight gain. Cardio- or cerebrovascular disease. Monitor BP in children and adolescents initially and during therapy. Increased risk of QT prolongation (eg, family history, cardiovascular disease, elderly, CHF, heart hypertrophy). Avoid in cardiac arrhythmias (eg, bradycardia), hypokalemia, hypomagnesemia, congenital prolongation of the QT interval. Pre-existing low WBCs or history of leukopenia/neutropenia; monitor CBCs during 1st few months of treatment; discontinue if WBCs decline. Hepatic dysfunction. Seizure risk. Risk of aspiration pneumonia. Exposure to extreme heat. Dehydration. Hypovolemia. Urinary retention. Significant prostatic hypertrophy. Perform fall risk assessments when initiating and recurrently on long-term therapy. Do eye exam initially and every 6 months. History of breast cancer. Reevaluate periodically. Avoid abrupt cessation. Write ℞ for smallest practical amount. Debilitated. Neonates: risk of extrapyramidal and/or withdrawal symptoms post delivery (due to exposure during 3rd-trimester pregnancy). Pregnancy. Nursing mothers.

    Seroquel Xr Pharmacokinetics

    See Literature

    Seroquel Xr Interactions Interactions

    Avoid drugs that prolong QT interval including Class 1A (eg, quinidine, procainamide) or Class III antiarrhythmics (eg, amiodarone, sotalol), antipsychotics (eg, ziprasidone, chlorpromazine, thioridazine), antibiotics (eg, gatifloxacin, moxifloxacin), and others (eg, pentamidine, methadone, levomethadyl acetate). Potentiates CNS effects with alcohol (avoid), other CNS depressants. Potentiated by CYP3A4 inhibitors (eg, azole antifungals, indinavir, ritonavir, nefazodone, others); adjust dose. Antagonized by CYP3A4 inducers (eg, phenytoin, carbamazepine, phenobarbital, rifampin, avasimibe, St. John's wort); adjust dose. Potentiates antihypertensives, lorazepam. Antagonizes effects of levodopa, dopamine agonists. Caution with drugs having anticholinergic effects.

    Seroquel Xr Adverse Reactions Adverse Reactions

    Somnolence, dry mouth, constipation, dizziness, increased appetite, dyspepsia, weight gain, fatigue, dysarthria, nasal congestion, asthenia, abdominal pain, postural hypotension, pharyngitis, lethargy, hyperglycemia, hypothyroidism, hyperprolactinemia; increased ALT (transient), total cholesterol +/or triglycerides; leukopenia, neutropenia, agranulocytosis, intestinal obstruction; rarely: tardive dyskinesia (consider discontinuation), neuroleptic malignant syndrome.

    Seroquel Xr Clinical Trials

    See Literature

    Seroquel Xr Note

    Not Applicable

    Seroquel Xr Patient Counseling

    See Literature

    Seroquel Xr Generic Name & Formulations General Description

    Quetiapine (as fumarate) 50mg, 150mg, 200mg, 300mg, 400mg; ext-rel tabs.

    Pharmacological Class

    Dibenzothiazepine.

    How Supplied

    XR—60; Tabs 25mg, 50mg, 100mg, 200mg, 400mg—100; 300mg—60

    Seroquel Xr Indications Indications

    Schizophrenia.

    Seroquel Xr Dosage and Administration Adult

    Swallow whole. Take on an empty stomach or with light meal. Initially 300mg once daily in the PM; may increase at 1-day intervals in increments of up to 300mg/day. Usual range: 400–800mg/day; max 800mg/day. Maintenance: 400–800mg/day. Elderly, debilitated, or risk of postural hypotension: titrate more slowly to lower target dose. Elderly or hepatic impairment: initially 50mg/day; may increase in increments of 50mg/day. Concomitant CYP3A4 inhibitors or inducers, reinitiation of treatment: see full labeling. Switching from Seroquel immediate-release: give XR at equivalent total daily dose taken once daily.

    Children

    <13yrs: not established. Swallow whole. Take on an empty stomach or with light meal. Give once daily in the PM. 13–17yrs: 50mg on day 1, then 100mg on day 2, then 200mg on day 3, then 300mg on day 4, then 400mg on day 5; may further increase up to target range of 400–800mg/day; max 800mg/day. Maintenance: <18yrs: not established.

    Seroquel Xr Contraindications

    Not Applicable

    Seroquel Xr Boxed Warnings Boxed Warning

    Increased mortality in elderly patients with dementia-related psychosis. Suicidal thoughts and behaviors.

    Seroquel Xr Warnings/Precautions Warnings/Precautions

    Elderly with dementia-related psychosis (not approved use); increased risk of death or cerebrovascular events (eg, stroke, TIA). Increased risk of suicidal thoughts and behavior in children, adolescents, and young adults; monitor closely for worsening or unusual changes in all patients. Exclude neuroleptic malignant syndrome if fever or other symptoms occur. Diabetes. Monitor for hyperglycemia, hyperlipidemia: do fasting blood glucose and lipids testing initially and during therapy. Monitor for weight gain. Cardio- or cerebrovascular disease. Monitor BP in children and adolescents initially and during therapy. Increased risk of QT prolongation (eg, family history, cardiovascular disease, elderly, CHF, heart hypertrophy). Avoid in cardiac arrhythmias (eg, bradycardia), hypokalemia, hypomagnesemia, congenital prolongation of the QT interval. Pre-existing low WBCs or history of leukopenia/neutropenia; monitor CBCs during 1st few months of treatment; discontinue if WBCs decline. Hepatic dysfunction. Seizure risk. Risk of aspiration pneumonia. Exposure to extreme heat. Dehydration. Hypovolemia. Urinary retention. Significant prostatic hypertrophy. Perform fall risk assessments when initiating and recurrently on long-term therapy. Do eye exam initially and every 6 months. History of breast cancer. Reevaluate periodically. Avoid abrupt cessation. Write ℞ for smallest practical amount. Debilitated. Neonates: risk of extrapyramidal and/or withdrawal symptoms post delivery (due to exposure during 3rd-trimester pregnancy). Pregnancy. Nursing mothers.

    Seroquel Xr Pharmacokinetics

    See Literature

    Seroquel Xr Interactions Interactions

    Avoid drugs that prolong QT interval including Class 1A (eg, quinidine, procainamide) or Class III antiarrhythmics (eg, amiodarone, sotalol), antipsychotics (eg, ziprasidone, chlorpromazine, thioridazine), antibiotics (eg, gatifloxacin, moxifloxacin), and others (eg, pentamidine, methadone, levomethadyl acetate). Potentiates CNS effects with alcohol (avoid), other CNS depressants. Potentiated by CYP3A4 inhibitors (eg, azole antifungals, indinavir, ritonavir, nefazodone, others); adjust dose. Antagonized by CYP3A4 inducers (eg, phenytoin, carbamazepine, phenobarbital, rifampin, avasimibe, St. John's wort); adjust dose. Potentiates antihypertensives, lorazepam. Antagonizes effects of levodopa, dopamine agonists. Caution with drugs having anticholinergic effects.

    Seroquel Xr Adverse Reactions Adverse Reactions

    Somnolence, dry mouth, constipation, dizziness, increased appetite, dyspepsia, weight gain, fatigue, dysarthria, nasal congestion, asthenia, abdominal pain, postural hypotension, pharyngitis, lethargy, hyperglycemia, hypothyroidism, hyperprolactinemia; increased ALT (transient), total cholesterol +/or triglycerides; leukopenia, neutropenia, agranulocytosis, intestinal obstruction; rarely: tardive dyskinesia (consider discontinuation), neuroleptic malignant syndrome.

    Seroquel Xr Clinical Trials

    See Literature

    Seroquel Xr Note

    Not Applicable

    Seroquel Xr Patient Counseling

    See Literature






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